Chromosomes that harbor dominant sex determination loci are predicted to erode over time—losing genes, accumulating transposable elements, degenerating into a functional wasteland and ultimately becoming extinct. The Drosophila melanogaster Y chromosome is fairly far along this path to oblivion. The few genes on largely heterochromatic Y chromosome are required for spermatocyte‐specific functions, but have no role in other tissues. Surprisingly, a recent paper shows that divergent Y chromosomes can substantially influence gene expression throughout the D. melanogaster genome.1 These results show (...) that variation on Y has an important influence on the deployment of the genome. BioEssays 30:409–411, 2008. © 2008 Wiley Periodicals, Inc. (shrink)

Empirical philosophers of science aim to base their philosophical theories on observations of scientific practice. But since there is far too much science to observe it all, how can we form and test hypotheses about science that are sufficiently rigorous and broad in scope, while avoiding the pitfalls of bias and subjectivity in our methods? Part of the answer, we claim, lies in the computational tools of the digital humanities, which allow us to analyze large volumes of scientific literature. Here (...) we advocate for the use of these methods by addressing a number of large-scale, justificatory concerns—specifically, about the epistemic value of journal articles as evidence for what happens elsewhere in science, and about the ability of DH tools to extract this evidence. Far from ignoring the gap between scientific literature and the rest of scientific practice, effective use of DH tools requires critical reflection about these relationships. (shrink)

Stephan Joubert has already made his mark in South Africa with his solid way of doing Theology. In this Festschrift, we wanted to accord recognition to him for what he has already made and for what he is currently doing with e-kerk. His book, Jesus Radical, Righteous, Relevant, having initially been written in Afrikaans, was translated in 2012 into English and depicts his heart for the followers of Jesus and the familia Dei, specifically in South Africa. This article is a (...) journey through this book, with the current dilemma in our country and worldwide in the back of our minds, namely, the coronavirus disease starting in 2019. CONTRIBUTION: This article forms part of the Special Collection which will serve as a Festschrift for Prof Stephan Joubert to honour him for the tremendous work that he has done in Theology in South Africa. I took his book, Jesus, Radical, Righteous, Relevant as basis and applied it to our current situation with COVID-19. (shrink)

The society in which we currently live and operate is globally the Fourth Industrial Revolution and locally our environment or community. Although we are still in a lag period between the 3IR and 4IR, the 4IR already has a global disruptive effect, with artificial intelligence being gradually implemented, with fluid contexts, and where nobody agrees on anything. Deep learning, unlearning and relearning must take place on a daily basis. The question could well be asked if there is any place for (...) the Bible and Christianity in this new vibrant global community.All theology is contextual. Although theology deals with what is most absolute in reality, citing Mellert, it is also relative in that there is never a final or last answer to most religious questions. The handbook and norm for our theology and religion is still the Bible – a compendium of books written approximately 2000 years ago with no new information added to it ever since. The challenge of the church is to make that information contextual in this ‘disruptive’ era and to bring the gospel in a new and fresh way to everybody without compromising the basic truths and normativity of the Bible.This article argues that the Bible should still take centre stage in the academic training of our theological students, in our preaching of the gospel on a daily basis, in our engagement with people in need and in the transformation of our societies in general. As the centre of Jesus’ preaching on earth was the kingdom of God, he also acted as the perfect example of how to establish the kingdom of God and the flourishing life on earth.Contribution: This is a more practical article and puts the notion of the significance of the Bible within the environment of the Fourth Industrial Revolution. As this is a disruptive era, it requires from us to also present the word of God in a ‘disruptive’ way. We will have to present the ‘old’ word of God in a brand-new way so as to make sure that the people of this era will grasp it. (shrink)

Post-school education in South Africa mostly takes place within an industrial-age factory environment as has been done for the past 50 years or longer. This is the case despite the fact that the world is on the brink of, or already part of, the Fourth Industrial Revolution, called by some an ‘emerging new world order’. Educating students today like we did it half a century ago has now become education to a ‘quickly vanishing world’. Although one may argue that the (...) content of Theology will not be much affected by the 4IR, it is proposed that the way in which that content is communicated and educated should change drastically. Doing this will prepare our students to become relevant preachers or theologians in the current postmodern society. The proposed model in this article is called an outside-in model – contrasted to the current inside-out model of education – in which our students should be taught to develop a sense of deep learning, to effectively learn and work in and with groups, to use their mobile devices and social media within the environment of education and to discuss new ways of gathering God’s people.The question that each educator should ask themselves nowadays is: Am I really preparing my students for the future that they are facing?Contribution: A new way of teaching Theology in the 4IR is imperative for our students. This article suggests how it could be done. Although this entails willpower and persuading the mostly ‘old’ lecturers in Theology to engage with real technology, it is all about the student, because many of these students will become the lecturers of tomorrow. Our faculties or departments of Theology are therefore urged to fit themselves into the new mould and to train our future theologians in a 4IR way. (shrink)

C. S. Peirce's indictment that "the chief cause of [metaphysics'] backward condition is that its leading professors have been theo (Collected Papers 6:3) falls heavily at my door. For it logians" was out of reflection upon religious experience and its meaning that the present relational metaphysic was conceived. My hope, however, is that its scope is sufficiently wider than its theological origins to justify its appearance as a work in philosophy. Having been nurtured in existential philosophy and having reached some (...) measure of maturity with the wise counsel of Professor Dr. Fritz Buri, of Basel, I came to feel that theology as a modern discipline had reached an impasse owing to its overextended commitments to a subject-object paradigm of thought. Even those theologians who despaired of these ties seemed unable to find an independent alternative idiom for their ideas. A second tension in my thinking resulted from the inordinate neglect by theologians of the natural world. Also, my natural interest in physical understanding seemed unfulfilled within the narrow confines of theology, even of philosophical theology as then practiced. As I turned decisively toward the study of modern physics, and especially of cosmology, a new world seemed to open up to me. After extensive study with prominent astronomers and physicists, it began to dawn on me that the new physics has devised conceptual paradigms of thought which could be generalized into a metaphysical system of universal interest. (shrink)

The chapters in this section of the volume reveal the striking variety of human numerical cognition. The section comprises four chapters that focus on different aspects of the representation of numerical knowledge, as well as three chapters that examine the several cognitive processes involved in the manipulation of numbers during simple mental arithmetic. They show how chronometric analyses, in combination with clever experimental designs, can reveal the cognitive processes and representations underlying this impressive collection of cognitive skills. Our goal in (...) this overview chapter is to highlight common themes that connect these contributions. In particular, we suggest links between the present contributions, all of which are firmly grounded in the traditional information-processing approach to the human mind, and the more recently emerged embodied cognition perspective, according to which all knowledge representations remain associated with those sensory and motor features that were activated during acquisition of that knowledge. (shrink)

The current behavioral consultation case demonstrates how functional behavioral assessment (FBA) data, basic and applied research, teacher preferences, and contextual variables contribute to the decision making process when developing classroom intervention procedures. A male, African-American, fifth-grade general education student was initially referred for his inappropriate vocalizations duringtime designated for independent seatwork. FBA data suggested that this behavior was being reinforced with teacher attention. Additional data showed that he was failing to complete his assignments. An intervention was implemented where the student (...) was given assignments one a time. He was instructed to solicit teacher attention and his next assignment after completing each assignment. Analysis ofteacher ratings for inappropriate vocalizations and assignment performance data suggest that the intervention was effective in increasing assignment completion and decreasing inappropriate verbalizations. Discussion focuses on how the various data playa role in the development and implementation of classroom intervention procedures. (shrink)

From the 15th century onwards, most of the countries in Africa have been colonised by theEuropean world powers, Great Britain, France, Portugal, Germany, Spain, Italy and Belgium.South Africa was officially colonised in 1652. Apart from the European colonisation beingexecuted from the south of the continent, South Africa also experienced a migration andinvasion of people groups from the north. The indigenous people groups, inhabiting thecountry long before these two groups arrived there, will be discussed as background to the restof the article. (...) A few factors that made the colonisation of South Africa unique within theAfrican context will be discussed. (shrink)

Concern for the rights and safety of individuals has caused clinical researchers to develop informed consent protocols for research involving human subjects. The applicapability of these regulations to social science research is often tenuous, since such research usually focuses on populations rather than individuals, and potential damage is apt to be political rather than personal. In cross-cultural social research, the protocols developed by Western clinical researchers may be not only ludicrously inapplicable, but intrusive and disruptive within the cultural context, raising (...) questions of the intellectual imperialism of Western research ethics. (shrink)

The year 2017 is the year in which the Reformation, started by Martin Luther, is celebrating its 500th birthday. This depicts a milestone in the life of the Church of the Reformation and also in the life of Christians worldwide. This is a good time to ponder on the epistemological question of the validity and necessity of the Reformation. If this question is answered in a positive way, then it could bring us to the realisation that the time is ripe (...) for an African Reformation. This article will argue that this is indeed the case. A reformation, transformation and change is needed for the African Christian context. However, the question could well be asked: Who will be the 'second Luther?'. (shrink)

In the book of Romans, also called ‘Paul’s Letter/Epistle to the Romans’, it is clear that Paul created a very close lexical semantic relation between the concepts πίστις/πιστεύω [faith, believe], δίκαιος/δικαιοσύνη [righteous, righteousness] and σωτηρία/σῴζω [salvation, save]. Although it is said that the theme of righteousness (by or through faith) is the focal point of Paul’s theology, especially in Romans, this term is very closely linked to the two concepts, faith and salvation, in this letter. The aim of this article (...) is to investigate that relation, specifically in the two passages of Romans 1:16–17 and 10:6a, 8b–10, in an attempt to come to an understanding of what Paul had in mind when he used these three terms together in these passages. (shrink)

This article examines a neglected ancient source for desire between women that nonetheless has a rich reception history in the context of female homoeroticism: the Callisto episode in Ovid’s Metamorphoses. The article argues that the relationship between Diana and her hunting companion Callisto can be read as homoerotic and that, unlike many ancient accounts of female-female eroticism, neither character is represented as a tribas (a gender-deviant “woman” with a masculinized body, who seeks to penetrate other women). The Callisto episode is (...) therefore an invaluable piece of evidence for ancient discourses on sexuality exceeding the bounds of the active/passive model. (shrink)

In South Africa, the implementation of serious games and gamification in the design of curricula, being presented in schools and institutions of higher education, is mostly a novelty. As we are in a transitional phase with education, especially on two levels, namely, with the decolonisation of education and preparing education for the Fourth Industrial Revolution, it would be fitting and high time to fully implement gaming into the curricula. This article takes a look at the implementation of a serious game (...) on an undergraduate level at a residential university. It focuses in a pragmatic way on applying the serious game on biblical languages – Greek, Hebrew and Latin – proposing that they should be presented to the student as paper behind the glass. (shrink)